Serato recommends that mixers & audio interfaces are connected directly to the laptop for stable performance.
I know this may not be possible with Macbook Pro 13 that has only 2 USB C ports.
You may want to consider a Thunderbolt 3 dock
something like
This bypasses the USB Bus or something.
Could be the USB hub or latency in Serato.
Are you using Pitch N Time in Serato?
Whats the spec of the Macbook pro? RAM, CPU?
The USB ports on the X1800 looks like USB 2.0
Was that the USB cable you were supplied with?
The SC5000/M have USB 3.0 ports on the rear, why are you not using the blue USB cable that it came with.
USB 3.0 looks like this
Not that i have noticed. If going by the discussed to death topic of high end roll off, then perhaps Serato may even sound better than playing on the Primes. But like i said, they sound the same to me and they sound good both at home and at venues with EV + Crown and Void Acoustics sound systems
Have you considered OBS?
